The Secret to More Energy and Youthful Aging: NAD Supplements
NAD and Anti-Aging: Can It Reverse the Clock?
NAD+ levels can drop by more than 50% by the time you reach your 40s. This natural decrease plays a significant role in how you may experience aging, as it affects everything from energy production to the body’s ability to repair itself.[1]
Interest in NAD+ supplementation has surged, especially among those seeking natural, holistic ways to maintain vitality, mental clarity, and a youthful appearance. But what exactly is NAD+, and how does it work for anti-aging?
This article will answer your most pressing questions about NAD+ to help you make informed decisions about your health.
What Is NAD+ and What Does It Do for the Body?
NAD+, short for nicotinamide adenine dinucleotide, is a coenzyme that helps convert food into the cellular energy your body needs for everything from physical movement to brain function. It also supports metabolic health by regulating how your cells use nutrients and manage waste, and it plays a critical role in maintaining cellular integrity.
Because NAD+ is so closely tied to cellular energy and repair, its decline can contribute to the common signs of aging—fatigue, decreased mental clarity, slower metabolism, and skin changes. By supporting healthy NAD+ levels, you can give your body the foundation it needs to age well.
Does NAD+ Reverse Aging?
NAD+ plays a crucial role in DNA repair, helping your cells fix damage that accumulates over time. It also supports mitochondrial function, and when mitochondria function well, your cells are better equipped to handle stress.[2]
Research also highlights the role of NAD+ in activating sirtuins, a family of proteins that regulate inflammation response, protect cellular health, and influence metabolic processes linked to biological age.[3]
While NAD+ supplementation won’t erase age or make you biologically younger overnight, it can support your body’s natural ability to maintain and rejuvenate itself. Supplementing with NAD+ may give you more energy, sharper mental clarity, and healthier cells[3]—key factors that can help you feel better with age.
Can NAD+ Make You Look Younger or Improve Skin Health?
NAD+ contributes to healthier skin by encouraging skin cell turnover—the process by which old, damaged cells are replaced with fresh, new ones. Additionally, collagen synthesis slows as natural NAD+ levels decline, which can lead to wrinkles and loss of skin firmness.[4] By boosting NAD+, you can help your skin maintain its structural integrity longer.
NAD+ also supports your cells’ ability to neutralize oxidative stress—damage caused by free radicals and environmental toxins. In doing so, it can help manage inflammation and premature signs of aging.[4]
Although NAD+ supports the biological processes behind youthful skin, it won’t stop or turn back the clock. Think of it as one part of your holistic approach to graceful aging.
What Are the Top NAD+ Benefits for Women?
Women experience unique challenges as they age, from fluctuating hormone levels to changes in metabolism and energy. NAD+ can help combat the fatigue and sluggishness many women face during hormonal shifts, especially in their 30s to 50s.
NAD+ plays a part in hormone balance by influencing cellular communication and repair. While it’s not a hormone itself, supplementing with NAD+ can help your body regulate hormones more effectively for more stable moods and energy levels.[5]
Research indicates that NAD+ can also help regulate your stress response by activating sirtuins and other protective enzymes.[2] This effect can be particularly beneficial for women juggling multiple roles and facing chronic stress.
What’s the Best NAD+ Supplement?
With growing interest in NAD+ supplementation, the market has become crowded with options. Choosing the right supplement requires a careful look at a few key factors.
- Pure Formulas. Your body deserves clean supplements free from synthetic additives, fillers, and unnecessary chemicals. Look for formulas that are made by companies with a commitment to quality and transparency.
- Advanced Delivery Method. NAD+ is a delicate molecule, and how it’s delivered can impact how well your body uses it. Look for liquid formulas with advanced delivery systems that are designed to enhance bioavailability and absorption.
- Rigorous Testing. Carefully read labels, and seek out companies that will share third-party testing results, Certificates of Analysis, and clear information about how their products are made.
Global Healing Natural NAD+ Supplement
Our NAD+ supplement is formulated with your health and values in mind.
✓ Bioidentical NAD+ in its active form—no precursors or conversion steps needed
✓ MicroSomal® advanced delivery system for enhanced absorption and bioavailability
✓ Rigorous third-party testing and trusted quality certifications
Rather than chasing quick fixes, think of NAD+ as a foundational tool in your long-term wellness strategy. When combined with nourishing food, movement, sleep, and self-care, NAD+ supplementation can become a meaningful part of a holistic approach to aging well.
FAQ
Is NAD+ safe to take every day?
Yes. NAD+ supplements are generally well-tolerated and safe for daily use.[6] Always follow the recommended dosage and consult your healthcare provider if you’re pregnant, nursing, or taking medication.
When will I start to feel the benefits of NAD+?
Some people notice improvements in energy, focus, and overall well-being within a few weeks of consistent use.[6] However, results vary depending on your individual biology, lifestyle, and baseline NAD+ levels.
Can I get NAD+ from food alone?
While certain foods, like cucumbers and cabbage, contain NAD+ intermediates, it’s difficult to maintain optimal levels through diet alone.[7] Supplementation offers a more direct and effective way to restore and sustain NAD+ levels.
†Results may vary. Information and statements made are for education purposes and are not intended to replace the advice of your doctor. If you have a severe medical condition or health concern, see your physician.
References (7)
- McReynolds, M. R., Chellappa, K., & Baur, J. A. (2020). Age-related NAD+ decline. Experimental Gerontology, 134, 110888. https://doi.org/10.1016/j.exger.2020.110888
- Eisner, V., Picard, M., & Hajnóczky, G. (2018). Mitochondrial dynamics in adaptive and maladaptive cellular stress responses. Nature Cell Biology, 20(7), 755–765. https://doi.org/10.1038/s41556-018-0133-0
- Zhao, Y., Zhang, J., Zheng, Y., Zhang, Y., Zhang, X. J., Wang, H., Du, Y., Guan, J., Wang, X., & Fu, J. (2021). NAD+ improves cognitive function and reduces neuroinflammation by ameliorating mitochondrial damage and decreasing ROS production in chronic cerebral hypoperfusion models through Sirt1/PGC-1α pathway. Journal of Neuroinflammation, 18(1). https://doi.org/10.1186/s12974-021-02250-8
- Conlon, N. J. (2021). The Role of NAD+ in Regenerative Medicine. Plastic & Reconstructive Surgery, 150, 41S48S. https://doi.org/10.1097/prs.0000000000009673
- Li, L., Zhou, X., Liu, W., Chen, Z., Xiao, X., & Deng, G. (2024). Supplementation with NAD+ and its precursors: A rescue of female reproductive diseases. Biochemistry and Biophysics Reports, 38, 101715–101715. https://doi.org/10.1016/j.bbrep.2024.101715
- Freeberg, K. A., Udovich, C. C., Martens, C. R., Seals, D. R., & Craighead, D. H. (2023). Dietary Supplementation With NAD+-Boosting Compounds in Humans: Current Knowledge and Future Directions. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 78(12), 2435–2448. https://doi.org/10.1093/gerona/glad106
- Poljsak, B., Kovač, V., & Milisav, I. (2020). Healthy Lifestyle Recommendations: Do the Beneficial Effects Originate from NAD+ Amount at the Cellular Level? Oxidative Medicine and Cellular Longevity, 2020, 1–12. https://doi.org/10.1155/2020/8819627
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Dr. Edward Group, DC
FOUNDER | HEALER | ADVOCATEDr. Group, DC is a healer and alternative health advocate, and an industry leader and innovator in the field of natural health who is dedicated to helping others. He is a registered doctor of chiropractic (DC), a naturopathic practitioner (NP), and proud alum of Harvard Business School and MIT Sloan School of Management. Dr. Group, DC is the founder of Global Healing – a mission and vision he has shared through best-selling books and frequent media appearances. He aims to spread his message of positivity, hope, and wellness throughout the world.
